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Disruptores endocrinos presentes en perfumes y su efecto en la salud humana

dc.contributor.advisorCifuentes Prieto, Patricia
dc.contributor.authorRodríguez Bautista, Erika Natalia
dc.contributor.authorRodríguez Charry, Lizeth Valeria
dc.date.accessioned2023-04-13T16:20:38Z
dc.date.available2023-04-13T16:20:38Z
dc.date.issued2022-11
dc.identifier.urihttps://repositorio.universidadmayor.edu.co/handle/unicolmayor/6519
dc.description.abstractEn los últimos años el consumo de perfumes ha aumentado, por ello las industrias han optado por el uso de productos sintéticos que reducen costos y mejoran la calidad del producto final. Muchos de esos componentes se han identificado como disruptores endocrinos los cuales afectan la homeostasis del cuerpo porque pueden ejercer un efecto agonista o antagonista en diferentes ejes hormonales, que a su vez genera diferentes efectos en la salud como lo son problemas reproductivos, problemas metabólicos, cáncer, algunos se han descrito como obesógenos, entre otros convirtiéndose en un factor predisponente para la presentación de enfermedades. En este trabajo se realizó una revisión documental en diferentes bases de datos, donde se identificaron como principales disruptores endocrinos en perfumes a los ftalatos (DEP y DEPH), parabenos, almizcles sintéticos (almizcles macrocíclicos y policíclicos), igualmente estas sustancias y sus metabolitos han sido encontrados en diferentes muestras, especialmente orina, lo cual ha sido relacionado con el uso de fragancias. Asimismo, se ha identificado un mayor riego de exposición de estos compuestos en mujeres por la frecuencia de uso productos perfumados y en poblaciones vulnerables a cambios hormonales como los niños y mujeres en embarazo.spa
dc.description.tableofcontentsÍndice de figuras 6 Índice de tablas 7 Resumen 8 Introducción 9 1. Antecedentes 11 2. Marco teórico.17 2.1 Bases teóricas .17 2.1.2 Disruptor endocrino. .17 2.1.3 Efectos de los disruptores endocrinos en la salud 18 2.1.4 Tipos de disruptores endocrinos ....20 2.1.6 Disruptores endocrinos presentes en perfumes 21 2.1.7 Absorción de los disruptores endocrinos ...24 2.1.8 Perfumes..27 2.1.8.1 Clasificación..28 2.1.8.2 Componentes. ...28 3. Diseño metodológico 32 3.1 Tipo de investigación...32 3.2 Universo, población y muestra .32 3.3 Técnicas y procedimientos ..32 4. Resultados 34 5. Discusión 38 5.1 Sustancias que actúan como disruptores endocrinos en perfumes..38 5.2 Efectos sobre la salud .39 5.3 Medición de disruptores endocrinos y sus metabolitos en humanos 41 5.4 Poblaciones afectadas.43 5 5.5 Técnicas..45 5.6 Tipos de disruptores 46 6. Conclusiones 47 7. Referencias bibliográficas 48 8. Anexos 59 Anexo 1: Clasificación por categoría de la bibliografía encontrada con respecto a los disruptores endocrinos en perfumes ...59spa
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dc.format.mimetypeapplication/pdfspa
dc.language.isospaspa
dc.publisherUniversidad Colegio Mayor de Cundinamarcaspa
dc.rightsDerechos Reservados - Universidad Colegio Mayor de Cundinamarca, 2022spa
dc.rights.urihttps://creativecommons.org/licenses/by-nc-sa/4.0/spa
dc.titleDisruptores endocrinos presentes en perfumes y su efecto en la salud humanaspa
dc.typeTrabajo de grado - Pregradospa
dc.description.degreelevelPregradospa
dc.description.degreenameBacteriólogo(a) y Laboratorista Clínicospa
dc.publisher.facultyFacultad de Ciencias de la Saludspa
dc.publisher.placeBogotaspa
dc.publisher.programBacteriología y Laboratorio Clínicospa
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dc.rights.creativecommonsAtribución-NoComercial-CompartirIgual 4.0 Internacional (CC BY-NC-SA 4.0)spa
dc.subject.proposalDisruptores endocrinosspa
dc.subject.proposalPerfumesspa
dc.subject.proposalEfectos en la saludeng
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Derechos Reservados - Universidad Colegio Mayor de Cundinamarca, 2022
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