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Disruptores endocrinos derivados de productos plásticos que generan riesgo de aparición de diabetes en población adulta

dc.contributor.advisorCifuentes Prieto, Patricia
dc.contributor.authorBedoya Muñoz, Ana María
dc.contributor.authorSosa Pisco, Angie Tatiana
dc.contributor.authorOspina Pinzón, Manuela
dc.date.accessioned2024-07-23T16:57:37Z
dc.date.available2024-07-23T16:57:37Z
dc.date.issued2024
dc.identifier.urihttps://repositorio.universidadmayor.edu.co/handle/unicolmayor/7020
dc.description.abstractLos perturbadores hormonales son compuestos, algunos de ellos derivados de actividades industriales, que imitan la acción de las hormonas y sus receptores. Ejemplos como los ftalatos y bisfenoles, presentes en productos plásticos de uso diario, pueden ser citotóxicos y difíciles de eliminar, aumentando así el riesgo de enfermedades metabólicas como la diabetes mellitus. Este estudio tiene como objetivo analizar los efectos negativos de la exposición a estos químicos, especialmente los disruptores endocrinos diabetogénicos, debido a su impacto en la programación metabólica y su asociación con la resistencia a la insulina. Estos compuestos disminuyen la sensibilidad a la insulina, afectan las células pancreáticas y alteran la tolerancia a la glucosa, por lo que su investigación es crucial para entender las consecuencias perjudiciales a largo plazo. La investigación se basa en fuentes documentales de diversas bases de datos, analizando estudios que exploran la relación entre disruptores endocrinos en plásticos y la diabetes mellitus en adultos. Se identificó que la exposición a estas sustancias en etapas tempranas puede afectar negativamente la salud en la adultez. Los metabolitos de estos compuestos se encuentran principalmente en muestras de orina, indicando el grado de exposición. En conclusión, es fundamental reducir la exposición a disruptores endocrinos para prevenir problemas metabólicos de salud a largo plazo.spa
dc.description.tableofcontentsResumen Introducción Antecedentes Marco teórico 1. Diabetes mellitus 1.1. Diabetes mellitus tipo 1: 1.2. Diabetes mellitus tipo 2: 2. El sistema endocrino y su relación con la diabetes mellitus. 3. Plásticos de uso cotidiano. 3.1 Producción de plásticos. 3.2 Aditivos para plásticos. 4. Conceptualización disruptores endocrinos. 4.1 Mecanismos de acción de los disruptores endocrinos. 4.2 Disruptores endocrinos diabetogénicos derivados de plásticos. 5. Efectos de los disruptores endocrinos en las diferentes etapas de la vida Diseño metodológico Resultados Discusión Conclusiones Referencias bibliográficasspa
dc.format.extent57p.spa
dc.format.mimetypeapplication/pdfspa
dc.language.isospaspa
dc.publisherUniversidad Colegio Mayor de Cundinamarcaspa
dc.rightsDerechos Reservados - Universidad Colegio Mayor de Cundinamarca, 2024spa
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/spa
dc.titleDisruptores endocrinos derivados de productos plásticos que generan riesgo de aparición de diabetes en población adultaspa
dc.typeTrabajo de grado - Pregradospa
dc.description.degreelevelPregradospa
dc.description.degreenameBacteriólogo(a) y Laboratorista Clínicospa
dc.publisher.facultyFacultad de Ciencias de la Saludspa
dc.publisher.programBacteriología y Laboratorio Clínicospa
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dc.rights.creativecommonsAtribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)spa
dc.subject.proposalDisruptores endocrinosspa
dc.subject.proposalDiabetes mellitusspa
dc.subject.proposalPlásticosspa
dc.subject.proposalFtalatosspa
dc.subject.proposalBisfenolesspa
dc.subject.proposalInsulinaspa
dc.subject.proposalGlucosaspa
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dc.type.coarversionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
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